Sh2d1b2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sh2d1b2
SH2 domain containing 1B2
MGI:3622649

3 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sh2d1b1/Sh2d1b2^tm1.1Cpt/Sh2d1b1/Sh2d1b2^tm1.1Cpt involves: BALB/cJ	decreased interferon-gamma secretion	J:166054
	impaired natural killer cell mediated cytotoxicity	J:166054
Sh2d1b2^tm1.1Cpt/Sh2d1b2^tm1.1Cpt involves: BALB/cJ * C57BL/6	impaired natural killer cell mediated cytotoxicity	J:166054
Sh2d1b2^tm1Vei/Sh2d1b2^tm1Vei involves: 129S1/Sv * 129X1/SvJ	impaired natural killer cell mediated cytotoxicity	J:145969
	increased natural killer cell mediated cytotoxicity	J:110195
Tg(CD2-Sh2d1b2)#Vei/0 B6.Cg-Tg(CD2-Sh2d1b2)#Vei	impaired natural killer cell mediated cytotoxicity	J:110195

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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