Best3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Best3
bestrophin 3
MGI:3580298

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Best3^tm1.1Zhoj/Best3^tm1.1Zhoj Tg(Cdh5-cre)1Spe/0 involves: 129S1/SvImJ * C57BL/6J	normal cardiovascular system phenotype	J:338981
Best3^tm1.1Zhoj/Best3^tm1.1Zhoj Tg(Tagln-cre)1Her/0 involves: C57BL/6 * SJL	abdominal aorta aneurysm	J:338981
	abnormal aorta elastic tissue morphology	J:338981
	abnormal aorta morphology	J:338981
	abnormal aorta tunica media morphology	J:338981
	abnormal aorta wall morphology	J:338981
	abnormal vascular smooth muscle physiology	J:338981
	aortic aneurysm	J:338981
	aortic dissection	J:338981
	aortitis	J:338981
	decreased aorta wall thickness	J:338981
	descending aorta dilation	J:338981
	dilated ascending aorta	J:338981
	increased apoptosis	J:338981
	increased susceptibility to induced morbidity/mortality	J:338981
	internal hemorrhage	J:338981
	premature death	J:338981
	thoracic aorta aneurysm	J:338981

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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