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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sle16
systematic lupus erythematosus susceptibility 16
MGI:3531330
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
C1qatm1Mjw/C1qatm1Mjw
Sle16129S6/SvEvTac/Sle16129S6/SvEvTac
involves: 129S/SvEv * 129X1/Sv * C57BL/6 		increased anti-chromatin antibody level J:118645
increased anti-double stranded DNA antibody level J:118645
increased anti-nuclear antigen antibody level J:118645
increased anti-single stranded DNA antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
C1qatm1Mjw/C1qatm1Mjw
Sle16129S6/SvEvTac/Sle16C57BL/6
involves: 129S/SvEv * 129X1/Sv * C57BL/6 		increased anti-chromatin antibody level J:118645
increased anti-double stranded DNA antibody level J:118645
increased anti-nuclear antigen antibody level J:118645
increased anti-single stranded DNA antibody level J:118645
increased susceptibility to systemic lupus erythematosus J:118645
Fcgr2btm1.2Jsv/Fcgr2btm1.2Jsv
Sle16C57BL/6/Sle16C57BL/6
involves: C57BL/6 * FVB/N 		abnormal adaptive immunity J:179175
abnormal glomerular capillary thrombosis J:179175
abnormal renal glomerulus morphology J:179175
albuminuria J:179175
normal immune system phenotype J:179175
increased immunoglobulin level J:179175
increased susceptibility to induced arthritis J:179175
kidney inflammation J:179175
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory