Tmtc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmtc3
transmembrane and tetratricopeptide repeat containing 3
MGI:3036255

13 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmtc3^{Gt(JST185)Byg}/Tmtc3^{Gt(JST185)Byg} involves: 129P2/OlaHsd * A/J	abnormal branching involved in lung morphogenesis	J:178869
	abnormal cell differentiation	J:178869
	abnormal lung bud morphology	J:178869
	abnormal lung development	J:178869
	cyanosis	J:178869
	impaired lung alveolus development	J:178869
	overexpanded pulmonary alveolus	J:178869
	postnatal growth retardation	J:178869
	postnatal lethality, incomplete penetrance	J:178869
	respiratory failure	J:178869
Tmtc3^{Gt(JST185)Byg}/Tmtc3^{Gt(JST185)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal branching involved in lung morphogenesis	J:178869
	abnormal cell differentiation	J:178869
	abnormal lung bud morphology	J:178869
	abnormal lung development	J:178869
	cyanosis	J:178869
	impaired lung alveolus development	J:178869
	overexpanded pulmonary alveolus	J:178869
	postnatal growth retardation	J:178869
	postnatal lethality, incomplete penetrance	J:178869
	respiratory failure	J:178869
Tmtc3^{tm1b(EUCOMM)Wtsi}/Tmtc3⁺ C57BL/6N-Tmtc3^{tm1b(EUCOMM)Wtsi}/Bay	abnormal sinus arrhythmia	J:211773
	increased heart rate variability	J:211773
Tmtc3^{tm1b(EUCOMM)Wtsi}/Tmtc3^{tm1b(EUCOMM)Wtsi} C57BL/6N-Tmtc3^{tm1b(EUCOMM)Wtsi}/Bay	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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