Lrrc4b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrrc4b
leucine rich repeat containing 4B
MGI:3027390

36 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrrc4b^em1(IMPC)J/Lrrc4b^em1(IMPC)J C57BL/6NJ-Lrrc4b^em1(IMPC)J/Mmjax	abnormal behavior	J:211773
	abnormal bone structure	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	increased anxiety-related response	J:211773
	increased hematocrit	J:211773
	increased thigmotaxis	J:211773
	increased vertical activity	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Lrrc4b^tm1Lex/Lrrc4b⁺ B6.129S-Lrrc4b^tm1Lex	decreased anxiety-related response	J:276446
Lrrc4b^tm1Lex/Lrrc4b⁺ B6.129S-Lrrc4b^tm1Lex	decreased locomotor activity	J:276446
Lrrc4b^tm1Lex/Lrrc4b^tm1Lex B6.129S-Lrrc4b^tm1Lex	abnormal brain morphology	J:276446
	abnormal eating behavior	J:276446
	normal behavior/neurological phenotype	J:276446
	decreased anxiety-related response	J:276446
	decreased body weight	J:276446
	enlarged lateral ventricles	J:276446
	enlarged third ventricle	J:276446
	impaired spatial learning	J:276446
	increased locomotor activity	J:276446
	increased vertical activity	J:276446
	lethality, incomplete penetrance	J:276446
	normal nervous system phenotype	J:276446
	postnatal growth retardation	J:276446
	postnatal lethality, incomplete penetrance	J:276446
	preweaning lethality, incomplete penetrance	J:276446
	reduced long-term potentiation	J:276446
Lrrc4b^tm1Lex/Lrrc4b^tm1Lex involves: 129S/SvEv * C57BL/6J	abnormal brain wave pattern	J:276446
	abnormal excitatory postsynaptic currents	J:276446
	normal behavior/neurological phenotype	J:276446
	decreased anxiety-related response	J:276446
	decreased body weight	J:276446
	decreased brain size	J:276446
	decreased excitatory postsynaptic current amplitude	J:276446
	decreased excitatory postsynaptic current frequency	J:276446
	decreased thigmotaxis	J:276446
	normal growth/size/body region phenotype	J:276446
	hyperactivity	J:276446
	impaired coordination	J:276446
	impaired spatial learning	J:276446
	increased excitatory postsynaptic current amplitude	J:276446
	increased susceptibility to pharmacologically induced seizures	J:276446
	increased vertical activity	J:276446
	normal mortality/aging	J:276446
	normal nervous system phenotype	J:276446
	reduced long-term potentiation	J:276446
	small thalamus	J:276446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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