Lclat1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lclat1
lysocardiolipin acyltransferase 1
MGI:2684937

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lclat1^em1(IMPC)Mbp/Lclat1^em1(IMPC)Mbp C57BL/6N-Lclat1^em1(IMPC)Mbp/MbpMmucd	increased circulating alanine transaminase level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773
	increased startle reflex	J:211773
Lclat1^tm1Arai/Lclat1^tm1Arai C57BL/6-Lclat1^tm1Arai	abnormal lipid homeostasis	J:183129
Lclat1^tm1Yugs/Lclat1^tm1Yugs B6.Cg-Lclat1^tm1Yugs	abnormal lipid homeostasis	J:163077
	abnormal mitochondrial ATP synthesis coupled electron transport	J:163077
	decreased brown adipose tissue mass	J:163077
	decreased brown fat cell lipid droplet size	J:163077
	decreased circulating glucose level	J:163077
	decreased circulating insulin level	J:163077
	decreased susceptibility to diet-induced obesity	J:163077
	decreased white adipose tissue mass	J:163077
	decreased white fat cell lipid droplet size	J:163077
	hyperactivity	J:163077
	increased energy expenditure	J:163077
	increased fatty acid oxidation	J:163077
	increased insulin sensitivity	J:163077
	increased oxygen consumption	J:163077
	increased respiratory quotient	J:163077
	polydipsia	J:163077
	polyphagia	J:163077

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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