Mir140 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mir140
microRNA 140
MGI:2676825

31 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mir140^em1Asah/Mir140^em1Asah involves: C57BL/6J * DBA	decreased cranium height	J:278573
Mir140^em1Tkob/Mir140⁺ C57BL/6-Mir140^em1Tkob	abnormal cartilage development	J:286036
	abnormal epiphyseal plate morphology	J:286036
	abnormal long bone epiphyseal plate morphology	J:286036
	delayed bone ossification	J:286036
	platyspondylia	J:286036
Mir140^em1Tkob/Mir140^em1Tkob C57BL/6-Mir140^em1Tkob	abnormal cartilage development	J:286036
	abnormal epiphyseal plate morphology	J:286036
	abnormal long bone epiphyseal plate morphology	J:286036
	decreased body size	J:286036
	decreased bone mineralization	J:286036
	delayed bone ossification	J:286036
	platyspondylia	J:286036
	short nasal bone	J:286036
	short snout	J:286036
	small vertebral body	J:286036
Mir140^tm1.1Asah/Mir140^tm1.1Asah involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal chondrocyte physiology	J:160358
	abnormal skeleton morphology	J:160358
	abnormal skeleton physiology	J:160358
	decreased body height	J:160358
	decreased body weight	J:160358
	decreased length of long bones	J:160358
	decreased long bone epiphyseal plate size	J:160358
	domed cranium	J:160358
	increased susceptibility to induced arthritis	J:160358
	osteoarthritis	J:160358
	postnatal growth retardation	J:160358
	short maxilla	J:160358
	short nasal bone	J:160358
	short snout	J:160358
	normal skeleton phenotype	J:160358
Mir140^tm1.1Tkob/Mir140^tm1.1Tkob involves: 129S4/SvJae * C57BL/6	decreased body size	J:286036
	short snout	J:286036
Mir140^tm1.1Tkob/Mir140^tm1.1Tkob involves: 129S4/SvJae * C57BL/6 * SJL	abnormal basicranium morphology	J:174096
	abnormal long bone epiphyseal plate morphology	J:174096
	abnormal skeleton development	J:174096
	decreased body size	J:174096
	decreased body weight	J:174096
	decreased cranium height	J:174096
	decreased length of long bones	J:174096
	decreased long bone epiphyseal plate size	J:174096
	increased width of hypertrophic chondrocyte zone	J:174096
	postnatal growth retardation	J:174096
	short femur	J:174096
	short tibia	J:174096
	small basisphenoid bone	J:174096
Tg(Col2a1-Mir140)#Asah/0 C57BL/6-Tg(Col2a1-Mir140)#Asah	decreased susceptibility to induced arthritis	J:160358

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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