Npas4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Npas4
neuronal PAS domain protein 4
MGI:2664186

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Npas4^tm1Meg/Npas4^tm1Meg involves: C57BL/6	hyperactivity	J:143367
	increased anxiety-related response	J:143367
	normal nervous system phenotype	J:143367
	premature death	J:143367
	seizures	J:143367
Npas4^tm1Ooe/Npas4⁺ involves: 129/Sv * C57BL/6	premature death	J:145569
Npas4^tm1Ooe/Npas4^tm1Ooe involves: 129/Sv * C57BL/6	abnormal behavior	J:145569
	abnormal neuron morphology	J:145569
	gliosis	J:145569
	increased susceptibility to neuronal excitotoxicity	J:145569
	increased susceptibility to xenobiotic induced morbidity/mortality	J:145569
	myoclonus	J:145569
	neuron degeneration	J:145569
	premature death	J:145569
Npas4^tm2Meg/Npas4^tm2Meg Not Specified	abnormal inhibitory postsynaptic currents	J:143367
Npas4^tm2Meg/Npas4^tm2Meg Not Specified	abnormal miniature excitatory postsynaptic currents	J:143367

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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