Ercc6l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
MGI:2654144

19 phenotypes from 2 alleles in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Ercc6l^tm1.1Ajlc/Y involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL/J	no abnormal phenotype detected	J:271028
Ercc6l^tm1.1Ajlc/Ercc6l⁺ involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL/J	no abnormal phenotype detected	J:271028
Ercc6l^tm1.1Ajlc/Ercc6l^tm1.1Ajlc involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL/J	normal no abnormal phenotype detected	J:271028
Ercc6l^tm1.2Ajlc/Y involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL/J	abnormal cell cycle checkpoint function	J:271028
	abnormal cell nucleus morphology	J:271028
	abnormal cell physiology	J:271028
	abnormal DNA replication	J:271028
	chromosomal instability	J:271028
	decreased embryo size	J:271028
	decreased fibroblast proliferation	J:271028
	early cellular replicative senescence	J:271028
	embryonic growth arrest	J:271028
	embryonic lethality during organogenesis, complete penetrance	J:271028
	increased brain apoptosis	J:271028
	increased embryonic tissue cell apoptosis	J:271028
	polyploidy	J:271028
Ercc6l^tm1.2Ajlc/Ercc6l⁺ involves: 129S2/SvPas * C57BL/6J * C57BL/6N * SJL/J	abnormal cell nucleus morphology	J:271028
	abnormal cell physiology	J:271028
	chromosomal instability	J:271028
	decreased fibroblast proliferation	J:271028
	decreased litter size	J:271028
	female infertility	J:271028
	lethality during fetal growth through weaning, incomplete penetrance	J:271028
	reduced female fertility	J:271028

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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