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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tph2
tryptophan hydroxylase 2
MGI:2651811
11 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Agrptm2(HBEGF)Rpa/Agrp+
Tph2tm1Mscl/Tph2tm1Mscl
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * C57BL/6NCr
abnormal eating behavior J:182577
abnormal postnatal growth/weight/body size J:182577
decreased serotonin level J:182577
Gsk3btm1Jrw/Gsk3b+
Tph2tm1Mca/Tph2tm1Mca
involves: 129 * 129S6/SvEvTac * C57BL/6J
abnormal social investigation J:131619
normal behavior/neurological phenotype J:131619
Tph1tm2Lex/Tph1tm2Lex
Tph2tm1Lex/Tph2tm1Lex
involves: 129S5/SvEvBrd * C57BL/6J
abnormal emotion/affect behavior J:144582
abnormal response to novel object J:144582
decreased body length J:144582
decreased body weight J:144582
decreased percent body fat/body weight J:144582
decreased serotonin level J:144582
decreased thermal nociceptive threshold J:144582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory