Tph2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tph2
tryptophan hydroxylase 2
MGI:2651811

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Agrp^{tm2(HBEGF)Rpa}/Agrp⁺ Tph2^tm1Mscl/Tph2^tm1Mscl involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * C57BL/6NCr	abnormal eating behavior	J:182577
	abnormal postnatal growth/weight/body size	J:182577
	decreased serotonin level	J:182577
Gsk3b^tm1Jrw/Gsk3b⁺ Tph2^tm1Mca/Tph2^tm1Mca involves: 129 * 129S6/SvEvTac * C57BL/6J	abnormal social investigation	J:131619
	normal behavior/neurological phenotype	J:131619
Tph1^tm2Lex/Tph1^tm2Lex Tph2^tm1Lex/Tph2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal emotion/affect behavior	J:144582
	abnormal response to novel object	J:144582
	decreased body length	J:144582
	decreased body weight	J:144582
	decreased percent body fat/body weight	J:144582
	decreased serotonin level	J:144582
	decreased thermal nociceptive threshold	J:144582

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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