Iqgap2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Iqgap2
IQ motif containing GTPase activating protein 2
MGI:2449975

10 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Iqgap2^{tm1b(KOMP)Wtsi}/Iqgap2^{tm1b(KOMP)Wtsi} C57BL/6N-Iqgap2^{tm1b(KOMP)Wtsi}/J	abnormal auditory brainstem response	J:211773
	decreased prepulse inhibition	J:211773
	increased startle reflex	J:211773
Iqgap2^tm1Vs/Iqgap2^tm1Vs either: 129S4/SvJae-Iqgap2^tm1Vs or B6.129S4-Iqgap2^tm1Vs	abnormal hepatocyte mitochondrial morphology	J:132670
	decreased hepatocyte number	J:132670
	increased circulating aspartate transaminase level	J:132670
	increased hemangioma incidence	J:132670
	increased hepatocellular carcinoma incidence	J:132670
	increased hepatocyte apoptosis	J:132670
	premature death	J:132670
Iqgap2^tm1Vs/Iqgap2^tm1Vs involves: 129S4/SvJae	increased hepatocellular carcinoma incidence	J:205882

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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