Arhgef10 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgef10
Rho guanine nucleotide exchange factor 10
MGI:2444453

14 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgef10^{tm1.1(KOMP)Vlcg}/Arhgef10^{tm1.1(KOMP)Vlcg} B6N(Cg)-Arhgef10^{tm1.1(KOMP)Vlcg}/J	decreased circulating glucose level	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating potassium level	J:211773
Arhgef10^tm1.1Ssfg/Arhgef10^tm1.1Ssfg B6.129S1-Arhgef10^tm1.1Ssfg	abnormal response to social novelty	J:271943
	abnormal social investigation	J:271943
	normal behavior/neurological phenotype	J:271943
	decreased anxiety-related response	J:271943
	decreased monoamine oxidase activity	J:271943
	increased coping response	J:271943
	increased dopamine level	J:271943
	increased locomotor activity	J:271943
	increased noradrenaline level	J:271943
	increased serotonin level	J:271943
	normal nervous system phenotype	J:271943

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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