Phf8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Phf8
PHD finger protein 8
MGI:2444341

25 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Phf8^{em2(IMPC)Wtsi}/Y C57BL/6N-Phf8^{em2(IMPC)Wtsi}/Wtsi	decreased erythrocyte cell number	J:211773
Phf8^{em2(IMPC)Wtsi}/Y C57BL/6N-Phf8^{em2(IMPC)Wtsi}/Wtsi	increased mean corpuscular hemoglobin	J:211773
Phf8^{em2(IMPC)Wtsi}/Phf8^{em2(IMPC)Wtsi} C57BL/6N-Phf8^{em2(IMPC)Wtsi}/Wtsi	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating LDL cholesterol level	J:211773
	increased mean corpuscular hemoglobin	J:211773
Phf8^tm1.1Cdcn/Y B6.129S6(Cg)-Phf8^tm1.1Cdcn	abnormal spatial reference memory	J:258245
	abnormal synaptic transmission	J:258245
	normal craniofacial phenotype	J:258245
	impaired contextual conditioning behavior	J:258245
	impaired passive avoidance behavior	J:258245
	impaired spatial learning	J:258245
	increased locomotor activity	J:258245
	reduced long-term potentiation	J:258245
Phf8^tm1.1Hoch/Y involves: 129S4/SvJae * C57BL/6	abnormal striatum morphology	J:248400
	normal craniofacial phenotype	J:248400
	decreased anxiety-related response	J:248400
	decreased cell proliferation	J:248400
	decreased thigmotaxis	J:248400
	normal growth/size/body region phenotype	J:248400
	increased coping response	J:248400
Phf8^tm1dIcs/Y C57BL/6N-Phf8^tm1dIcs/Ics	abnormal eye anterior chamber depth	J:211773
	improved glucose tolerance	J:211773
	increased circulating HDL cholesterol level	J:211773
Phf8^tm1dIcs/Phf8^tm1dIcs C57BL/6N-Phf8^tm1dIcs/Ics	abnormal eye anterior chamber depth	J:211773
	abnormal heart left ventricle morphology	J:211773
	decreased lymphocyte cell number	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased neutrophil cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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