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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lefty2
left-right determination factor 2
MGI:2443573
31 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lefty2tm1Hmd/Lefty2tm1Hmd
involves: 129P2/OlaHsd * C57BL/6Cr
abnormal developmental patterning J:57907
abnormal ectoderm development J:57907
abnormal embryo development J:57907
abnormal head fold morphology J:57907
abnormal primitive streak morphology J:57907
abnormal visceral yolk sac morphology J:57907
absent heart J:57907
absent notochord J:57907
absent primitive node J:57907
absent somites J:57907
absent vitelline blood vessels J:57907
embryonic lethality during organogenesis, complete penetrance J:57907
failure of chorioallantoic fusion J:57907
Lefty2tm2Hmd/Lefty2tm2Hmd
involves: 129P2/OlaHsd * C57BL/6
abnormal heart and great artery attachment J:70483
abnormal heart morphology J:70483
abnormal hepatic portal vein morphology J:70483
abnormal inferior vena cava morphology J:70483
abnormal large intestine placement J:70483
abnormal left-right axis patterning J:70483
abnormal liver morphology J:70483
absent heart right ventricle J:70483
accessory spleen J:70483
complete atrioventricular septal defect J:70483
dextrocardia J:70483
double outlet right ventricle J:70483
left atrial isomerism J:70483
left-sided isomerism J:70483
postnatal lethality, incomplete penetrance J:70483
normal respiratory system phenotype J:70483
transposition of great arteries J:70483
tricuspid valve atresia J:70483

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory