Kdm7a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kdm7a
lysine (K)-specific demethylase 7A
MGI:2443388

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kdm7a^em1Gpt/Kdm7a^em1Gpt Sp7^{tm1(icre)Bcgen}/Sp7⁺ involves: C57BL/6 * C57BL/6JGpt	abnormal fat cell differentiation	J:366478
	abnormal osteoclast differentiation	J:366478
	abnormal trabecular bone morphology	J:366478
	decreased bone marrow adipose tissue amount	J:366478
	decreased bone resorption	J:366478
	decreased bone trabecular spacing	J:366478
	decreased osteoclast cell number	J:366478
	decreased tumor necrosis factor (ligand) superfamily member 11 level	J:366478
	enhanced osteoblast differentiation	J:366478
	increased bone mineral content	J:366478
	increased bone mineralization	J:366478
	increased bone ossification	J:366478
	increased bone trabecula number	J:366478
	increased osteoblast cell number	J:366478
	increased trabecular bone mass	J:366478
	increased trabecular bone volume	J:366478
Kdm7a^{tm1a(EUCOMM)Wtsi}/Kdm7a^{tm1a(EUCOMM)Wtsi} C57BL/6N-Kdm7a^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal hair follicle bulge morphology	J:209956
	abnormal hair follicle morphology	J:209956
	abnormal sebaceous gland morphology	J:209956
	abnormal tail morphology	J:209956
	vertebral transformation	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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