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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Arhgef11
Rho guanine nucleotide exchange factor 11
MGI:2441869
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Arhgef11tm1Sgkd/Arhgef11+
Arhgef12tm1Sgkd/Arhgef12tm1Sgkd
involves: 129 * C57BL/6J
preweaning lethality, complete penetrance J:198274
Arhgef11tm1Sgkd/Arhgef11tm1Sgkd
Arhgef12tm1Sgkd/Arhgef12+
involves: 129 * C57BL/6J
preweaning lethality, incomplete penetrance J:198274
Arhgef11tm1Sgkd/Arhgef11tm1Sgkd
Arhgef12tm1Sgkd/Arhgef12tm1Sgkd
involves: 129 * C57BL/6J
abnormal brain vasculature morphology J:198274
abnormal embryonic erythrocyte morphology J:198274
abnormal fibroblast proliferation J:198274
abnormal placental labyrinth vasculature morphology J:198274
abnormal vascular development J:198274
abnormal vitelline vasculature morphology J:198274
decreased embryo size J:198274
decreased fibroblast proliferation J:198274
disorganized yolk sac vascular plexus J:198274
normal embryo phenotype J:198274
embryonic lethality during organogenesis, complete penetrance J:198274
enlarged pericardium J:198274
thin placenta labyrinth J:198274

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory