Sctr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sctr
secretin receptor
MGI:2441720

30 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sctr^tm1Bkcc/Sctr^tm1Bkcc B6.129S7-Sctr^tm1Bkcc	abnormal circulating antidiuretic hormone level	J:166370
	abnormal cytokine secretion	J:121376
	abnormal drinking behavior	J:166370
	abnormal kidney cortex morphology	J:121376
	abnormal kidney medulla morphology	J:121376
	abnormal response/metabolism to endogenous compounds	J:166370
	decreased urine creatinine level	J:121376
	decreased urine osmolality	J:121376
	decreased urine potassium level	J:121376
	decreased urine sodium level	J:121376
	decreased urine urea nitrogen level	J:121376
	dilated kidney collecting duct	J:121376
	expanded mesangial matrix	J:121376
	glomerulosclerosis	J:121376
	increased circulating glucose level	J:121376
	increased glomerular capsule space	J:121376
	increased macrophage cell number	J:121376
	kidney inflammation	J:121376
	polydipsia	J:121376
	polyuria	J:121376
Sctr^tm1Brd/Sctr^tm1Brd involves: 129S7/SvEvBrd * C57BL/6J	abnormal CNS synaptic transmission	J:114853
	abnormal dendritic spine morphology	J:114853
	abnormal excitatory postsynaptic potential	J:114853
	abnormal hippocampal pyramidal neuron dendrite morphology	J:114853
	abnormal social recognition	J:114853
	abnormal social/conspecific interaction behavior	J:114853
	impaired coordination	J:114853
	impaired spatial learning	J:114853
	increased locomotor activity	J:114853
	reduced long-term potentiation	J:114853

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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