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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rspo1
R-spondin 1
MGI:2183426
28 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rspo1tm1.1(KOMP)Vlcg/Rspo1tm1.1(KOMP)Vlcg
C57BL/6N-Rspo1tm1.1(KOMP)Vlcg/Ucd
abnormal kidney morphology J:211773
abnormal testis morphology J:211773
abnormal vibrissa morphology J:211773
decreased brain weight J:211773
decreased total body fat amount J:211773
female infertility J:211773
increased bone mineral content J:211773
increased grip strength J:211773
increased lean body mass J:211773
small testis J:211773
Rspo1tm1.1Ktom/Rspo1tm1.1Ktom
involves: C57BL/6 * CBA
abnormal ovary development J:133934
abnormal ovary secretion J:133934
decreased mature ovarian follicle number J:133934
decreased oocyte number J:133934
pseudohermaphroditism J:133934
reduced female fertility J:133934
Rspo1tm1Mcch/Rspo1tm1Mcch
involves: 129 * C57BL/6J
abnormal female meiosis J:133933
abnormal ovary development J:133933
pseudohermaphroditism J:133933
Rspo1tm1Mcch/Rspo1tm1Mcch
involves: 129/Sv * C57BL/6J
abnormal germ cell morphology J:203797
abnormal oogenesis J:203797
decreased oocyte number J:203797
decreased primordial ovarian follicle number J:203797
Rspo1tm2b(KOMP)Wtsi/Rspo1tm2b(KOMP)Wtsi
C57BL/6N-Rspo1tm2b(KOMP)Wtsi/Ics
abnormal eye anterior chamber depth J:211773
abnormal retina outer nuclear layer morphology J:211773
abnormal vitreous body morphology J:211773
decreased lean body mass J:211773
decreased total retina thickness J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating creatinine level J:211773
increased lymphocyte cell number J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory