Tlr8 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tlr8
toll-like receptor 8
MGI:2176887

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tlr8/Tlr7^tm1Vlcg/Tlr7⁺ Tlr8/Tlr7^tm1Vlcg/Tlr8^tm1Vlcg B6.Cg-Tlr8/Tlr7^tm1Vlcg Tlr8^tm1Vlcg	abnormal spleen marginal zone morphology	J:165267
	decreased anti-insulin autoantibody level	J:165267
	decreased IgG level	J:165267
	decreased IgM level	J:165267
	decreased marginal zone B cell number	J:165267
	increased IgG level	J:165267
	increased IgM level	J:165267
	increased marginal zone B cell number	J:165267
Tlr8/Tlr7^tm1Vlcg/Tlr8/Tlr7^tm1Vlcg B6.Cg-Tlr8/Tlr7^tm1Vlcg	decreased anti-insulin autoantibody level	J:165267
	decreased follicular B cell number	J:165267
	increased marginal zone B cell number	J:165267

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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