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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Helq
helicase, POLQ-like
MGI:2176740
29 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Helqem1(IMPC)Mbp/Helqem1(IMPC)Mbp
C57BL/6N-Helqem1(IMPC)Mbp/MbpMmucd
abnormal caudal vertebrae morphology J:211773
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
decreased bone mineral content J:211773
decreased lean body mass J:211773
enlarged spleen J:211773
female infertility J:211773
increased total body fat amount J:211773
male infertility J:211773
small kidney J:211773
small testis J:211773
HelqGt(RRF112)Byg/Helq+
involves: 129P2/OlaHsd * C57BL/6
abnormal ovary morphology J:206104
absent mature ovarian follicles J:206104
decreased mature ovarian follicle number J:206104
increased Harderian gland tumor incidence J:206104
increased intestinal adenoma incidence J:206104
increased pituitary adenoma incidence J:206104
ovary atrophy J:206104
ovary cyst J:206104
HelqGt(RRF112)Byg/HelqGt(RRF112)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal spermatogonia morphology J:206104
decreased litter size J:206104
increased gland tumor incidence J:206104
increased granulosa cell tumor incidence J:206104
increased Harderian gland tumor incidence J:206104
increased mammary gland tumor incidence J:206104
increased ovary tumor incidence J:206104
increased pituitary adenoma incidence J:206104
ovary atrophy J:206104
ovary cyst J:206104
reduced fertility J:206104
small testis J:206104
testicular atrophy J:206104

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory