Cln6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cln6
ceroid-lipofuscinosis, neuronal 6
MGI:2159324

14 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cln6^nclf/Cln6^nclf B6.Cg-Cln6^nclf/J	abnormal nervous system morphology	J:211608
Cln6^nclf/Cln6^nclf involves: C57BL/6J * C57BL/10J * C3HeB/FeJLe	abnormal myelination	J:47292
	abnormal neuron physiology	J:47292
	astrocytosis	J:47292
	axon degeneration	J:47292
	hindlimb paresis	J:47292
	increased susceptibility to age-related retinal degeneration	J:47292
	paralysis	J:47292
	premature death	J:47292
	seizures	J:47292
Cln6^{tm1b(EUCOMM)Hmgu}/Cln6^{tm1b(EUCOMM)Hmgu} C57BL/6N-Cln6^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal retina morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased total body fat amount	J:211773
	increased heart weight	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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