Sesn1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sesn1
sestrin 1
MGI:2155278

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sesn1^{tm1a(EUCOMM)Wtsi}/Sesn1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal class switch recombination	J:240602
	abnormal effector T cell number	J:240602
	decreased B cell number	J:240602
	enlarged spleen	J:240602
	increased immunoglobulin level	J:240602
	increased interferon-gamma secretion	J:240602
	increased interleukin-2 secretion	J:240602
	increased myeloid cell number	J:240602
	increased NK T cell number	J:240602
	increased single-positive T cell number	J:240602
	increased splenocyte number	J:240602
	increased T cell proliferation	J:240602
Sesn1^{tm1b(EUCOMM)Wtsi}/Sesn1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Sesn1^{tm1b(EUCOMM)Wtsi}/J	increased aggression	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular volume	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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