About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sp7
Sp7 transcription factor 7
MGI:2153568
18 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Kdm7aem1Gpt/Kdm7aem1Gpt
Sp7tm1(icre)Bcgen/Sp7+
involves: C57BL/6 * C57BL/6JGpt 		abnormal fat cell differentiation J:366478
abnormal osteoclast differentiation J:366478
abnormal trabecular bone morphology J:366478
decreased bone marrow adipose tissue amount J:366478
decreased bone resorption J:366478
decreased bone trabecular spacing J:366478
decreased osteoclast cell number J:366478
decreased tumor necrosis factor (ligand) superfamily member 11 level J:366478
enhanced osteoblast differentiation J:366478
increased bone mineral content J:366478
increased bone mineralization J:366478
increased bone ossification J:366478
increased bone trabecula number J:366478
increased osteoblast cell number J:366478
increased trabecular bone mass J:366478
increased trabecular bone volume J:366478
Sp7tm1.1Rnis/Sp7+
Zfhx4tm1.1Rnis/Zfhx4tm1.1Rnis
involves: C57BL * C57BL/6NCrlj * CBA/JNCrlj * DBA 		abnormal endochondral bone ossification J:316165
decreased chondrocyte number J:316165
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory