Tmc2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmc2
transmembrane channel-like gene family 2
MGI:2151017

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tmc1^tm1.1Ajg/Tmc1⁺ Tmc2^tm1.1Ajg/Tmc2^tm1.1Ajg B6.129-Tmc2^tm1.1Ajg Tmc1^tm1.1Ajg	abnormal vestibuloocular dark reflex	J:184419
Tmc1^tm1.1Ajg/Tmc1^tm1.1Ajg Tmc2^tm1.1Ajg/Tmc2⁺ B6.129-Tmc2^tm1.1Ajg Tmc1^tm1.1Ajg	abnormal hair cell mechanoelectric transduction	J:184419
Tmc1^tm1.1Ajg/Tmc1^tm1.1Ajg Tmc2^tm1.1Ajg/Tmc2^tm1.1Ajg B6.129-Tmc2^tm1.1Ajg Tmc1^tm1.1Ajg	abnormal cochlear hair cell physiology	J:184419
	abnormal hair cell mechanoelectric transduction	J:184419
	abnormal hair cell physiology	J:184419
	abnormal vestibuloocular dark reflex	J:184419
	ataxia	J:184419
	circling	J:184419
	cochlear hair cell degeneration	J:184419
	cochlear inner hair cell degeneration	J:184419
	cochlear outer hair cell degeneration	J:184419
	deafness	J:184419
	head bobbing	J:184419
	impaired righting response	J:184419
	increased or absent threshold for auditory brainstem response	J:184419

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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