Spred2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spred2
sprouty-related EVH1 domain containing 2
MGI:2150019

27 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spred2^em1(IMPC)Mbp/Spred2^em1(IMPC)Mbp C57BL/6N-Spred2^em1(IMPC)Mbp/MbpMmucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased mean corpuscular volume	J:211773
	enlarged heart	J:211773
	enlarged kidney	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	enlarged stomach	J:211773
	fused cornea and lens	J:211773
	increased brain size	J:211773
	increased circulating bilirubin level	J:211773
	increased red blood cell distribution width	J:211773
Spred2^Gt(XB228)Byg/Spred2^Gt(XB228)Byg involves: 129P2/OlaHsd * C57BL/6	decreased body length	J:100826
	decreased body weight	J:100826
	decreased litter size	J:100826
	decreased long bone epiphyseal plate size	J:100826
	decreased width of hypertrophic chondrocyte zone	J:100826
	disproportionate dwarf	J:100826
	increased megakaryocyte cell number	J:100826
	short tibia	J:100826
Spred2^tm1Taga/Spred2^tm1Taga Not Specified	abnormal definitive hematopoiesis	J:90463
Spred2^tm1Taga/Spred2^tm1Taga Not Specified	increased megakaryocyte cell number	J:90463

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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