Prkaa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
MGI:2145955

26 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkaa1^tm1Sbj/Prkaa1^tm1Sbj involves: 129	abnormal circulating hormone level	J:147215
	abnormal erythrocyte osmotic lysis	J:147215
	decreased hematocrit	J:147215
	decreased mean corpuscular hemoglobin	J:147215
	hemolytic anemia	J:147215
	increased red blood cell distribution width	J:147215
	increased spleen weight	J:147215
	low mean erythrocyte cell number	J:147215
	reticulocytosis	J:147215
Prkaa1^tm1Sbj/Prkaa1^tm1Sbj involves: 129S2/SvPas	abnormal circulating hormone level	J:324163
	abnormal enzyme/coenzyme level	J:324163
	abnormal hormone level	J:324163
	abnormal secondary ovarian follicle morphology	J:324163
	abnormal testosterone level	J:324163
	decreased corpora lutea number	J:324163
	decreased litter size	J:324163
	decreased mature ovarian follicle number	J:324163
	decreased superovulation rate	J:324163
	impaired granulosa cell differentiation	J:324163
	impaired ovarian folliculogenesis	J:324163
	increased atretic ovarian follicle number	J:324163
	increased primary ovarian follicle number	J:324163
	increased secondary ovarian follicle number	J:324163
	increased tertiary ovarian follicle number	J:324163
	prolonged estrous cycle	J:324163
	reduced female fertility	J:324163
Prkaa1^tm1Sbj/Prkaa1^tm1Sbj involves: 129S2/SvPas * C57BL/6J	decreased muscle cell glucose uptake	J:87719

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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