Gls2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gls2
glutaminase 2 (liver, mitochondrial)
MGI:2143539

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gls2^em1(IMPC)Tcp/Gls2^em1(IMPC)Tcp C57BL/6N-Gls2^em1(IMPC)Tcp/Tcp	abnormal coat/ hair morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal sternum morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	enlarged urinary bladder	J:211773
	thrombocytosis	J:211773
Gls2^em1Xen/Gls2^em1Xen involves: C57BL/6NTac	decreased fasting circulating glucose level	J:271619
	decreased hepatic glucose production	J:271619
	increased circulating glucagon level	J:271619
	increased circulating glutamine level	J:271619
	increased pancreatic alpha cell number	J:271619

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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