Celf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Celf4
CUGBP, Elav-like family member 4
MGI:1932407

30 phenotypes from 4 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Celf4^Ff/Celf4⁺ involves: C57BL/6J	abnormal seizure response to electrical stimulation	J:123744
	decreased body size	J:123744
	hyperactivity	J:123744
	increased body weight	J:123744
	increased susceptibility to weight gain	J:123744
	seizures	J:123744
Celf4^Ff/Celf4^Ff involves: 129S1/Sv * C57BL/6J	premature death	J:123744
Celf4^Ff/Celf4^Ff involves: A/J * C57BL/6J	premature death	J:123744
Celf4^Ff/Celf4^Ff involves: BALB/cByJ * C57BL/6J	premature death	J:123744
Celf4^Ff/Celf4^Ff involves: C3H/HeJ * C57BL/6J	premature death	J:123744
Celf4^Ff/Celf4^Ff involves: C57BL/6J	decreased body size	J:123744
	neonatal lethality, incomplete penetrance	J:123744
	premature death	J:123744
	tonic-clonic seizures	J:123744
Celf4^Ff/Celf4^Ff involves: C57BL/6J * EL/EFrkJ	premature death	J:123744
Celf4^Ff/Celf4^Ff involves: C57BL/6J * FVB/NJ	absence seizures	J:123744
Celf4^Ff/Celf4^Ff involves: C57BL/6J * FVB/NJ	premature death	J:123744
Celf4^tm1.1Frk/Celf4^tm1.1Frk Emx1^tm1(cre)Krj/? involves: 129 * C57BL/6J	increased susceptibility to induction of seizure by inducing agent	J:19671
Celf4^tm1.1Frk/Celf4^tm1.1Frk Tg(CAG-cre/Esr1)5Amc/0 involves: 129 C57BL/6J	abnormal spike wave discharge	J:181678
	convulsive seizures	J:181678
Celf4^tm1.1Frk/Celf4^tm1.1Frk Tg(Camk2a-cre)1Lfr/0 involves: 129 * C57BL/6J	increased susceptibility to induction of seizure by inducing agent	J:194671
Celf4^tm1.1Frk/Celf4^tm1.1Frk Tg(Slc32a1-cre)2.1Hzo/0 involves: 129 * C57BL/6J * FVB	decreased susceptibility to induction of seizure by inducing agent	J:194671
Celf4^tm1.2Frk/Celf4⁺ 129S1.129(Cg)-Celf4^tm1.2Frk/Frk	tonic-clonic seizures	J:181678
Celf4^tm1.2Frk/Celf4^tm1.2Frk 129S1.129(Cg)-Celf4^tm1.2Frk/Frk	abnormal miniature excitatory postsynaptic currents	J:181678
	abnormal spike wave discharge	J:181678
	absence seizures	J:181678
	decreased body size	J:181678
	postnatal lethality, incomplete penetrance	J:181678
	seizures	J:181678
	tonic-clonic seizures	J:181678
Celf4^tm1.2Frk/Celf4^tm1.2Frk (B6.129(Cg)-Celf4^tm1.2Frk/Frk x 129S1.129(Cg)-Celf4^tm1.2Frk/Frk)F1	abnormal spike wave discharge	J:181678
	absence seizures	J:181678
Celf4^tm1.2Frk/Celf4^tm1.2Frk B6.129(Cg)-Celf4^tm1.2Frk/Frk	postnatal lethality, incomplete penetrance	J:181678
	seizures	J:181678
	tonic-clonic seizures	J:181678
Celf4^{tm1a(EUCOMM)Wtsi}/Celf4⁺ C57BL/6N-Celf4^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased circulating calcium level	J:211773
	decreased circulating cholesterol level	J:211773
	impaired glucose tolerance	J:211773
	increased circulating insulin level	J:211773
Celf4^{tm1a(EUCOMM)Wtsi}/Celf4^{tm1a(EUCOMM)Wtsi} C57BL/6N-Celf4^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal bile duct morphology	J:239583
	abnormal ductus venosus valve morphology	J:239583
	abnormal eye muscle morphology	J:239583
	abnormal vitelline vein topology	J:239583
	absent basilar artery segment	J:239583
	blood in lymph vessels	J:239583
	dual inferior vena cava	J:239583
	fetal growth retardation	J:239583
	no abnormal phenotype detected	J:239583
	preweaning lethality, complete penetrance	J:211773

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