Myh10 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myh10
myosin, heavy polypeptide 10, non-muscle
MGI:1930780

24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Myh10^tm2Rsad/Myh10^tm2Rsad Myh14^tm1Rsad/Myh14^tm1Rsad involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	abnormal centrosome morphology	J:168304
	abnormal fetal cardiomyocyte morphology	J:168304
	abnormal microtubule cytoskeleton morphology	J:168304
	abnormal mitosis	J:168304
	abnormal mitotic spindle morphology	J:168304
	cardiomyopathy	J:168304
	decreased fetal cardiomyocyte number	J:168304
	heart hypoplasia	J:168304
	lethality throughout fetal growth and development, complete penetrance	J:168304
Myh10^tm4Rsad/Myh10^tm4Rsad Myh14^tm1Rsad/Myh14^tm1Rsad involves: 129S6/SvEvTac * C57BL/6	abnormal myocardial fiber physiology	J:168304
	cardiac hypertrophy	J:168304
	cardiomyopathy	J:168304
Myh10^{tm6(Myh9/GFP)Rsad}/Myh10^{tm6(Myh9/GFP)Rsad} involves: 129S6/SvEvTac * C57BL/6	abnormal cardiac outflow tract development	J:245570
	abnormal cerebellar foliation	J:124610
	abnormal fetal cardiomyocyte morphology	J:124610
	abnormal neuronal migration	J:124610
	cardiac hypertrophy	J:124610
	cardiac interstitial fibrosis	J:124610
	decreased cardiac muscle contractility	J:124610
	decreased fetal cardiomyocyte number	J:124610
	decreased survivor rate	J:124610
	dilated cardiomyopathy	J:124610
	double outlet right ventricle	J:124610
	increased fetal cardiomyocyte size	J:124610
	increased myocardial fiber size	J:124610
	lethality throughout fetal growth and development, incomplete penetrance	J:124610
	normal nervous system phenotype	J:124610
	ventricular septal defect	J:124610

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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