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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Clcnkb
chloride channel, voltage-sensitive Kb
MGI:1930643
74 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Clcnkbem1(IMPC)Mbp/Clcnkbem1(IMPC)Mbp
C57BL/6NCrl-Clcnkbem1(IMPC)Mbp/MbpMmucd
abnormal bone structure J:211773
abnormal cholesterol homeostasis J:211773
abnormal heart morphology J:211773
abnormal heart shape J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal lymph node morphology J:211773
abnormal ovary morphology J:211773
abnormal pancreas morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal stomach morphology J:211773
abnormal urinary bladder morphology J:211773
decreased heart weight J:211773
decreased locomotor activity J:211773
decreased lymphocyte cell number J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
decreased total body fat amount J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged liver J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged urinary bladder J:211773
improved glucose tolerance J:211773
increased basophil cell number J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating calcium level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased fasting circulating glucose level J:211773
increased grip strength J:211773
increased lean body mass J:211773
increased neutrophil cell number J:211773
increased red blood cell distribution width J:211773
shortened QRS complex duration J:211773
small heart J:211773
small kidney J:211773
small testis J:211773
Clcnkbem1Haca/Clcnkbem1Haca
C57BL/6-Clcnkbem1Haca
abnormal kidney afferent arteriole morphology J:259681
abnormal kidney efferent arteriole morphology J:259681
abnormal kidney vasculature morphology J:259681
decreased circulating chloride level J:259681
decreased circulating potassium level J:259681
decreased physiological sensitivity to xenobiotic J:259681
decreased renal glomerular filtration rate J:259681
decreased urine osmolality J:259681
normal hearing/vestibular/ear phenotype J:259681
hypotension J:259681
hypovolemia J:259681
increased circulating renin level J:259681
increased urine chloride ion level J:259681
increased urine potassium level J:259681
increased urine prostaglandin level J:259681
increased urine sodium level J:259681
polyuria J:259681
postnatal growth retardation J:259681
Clcnkbtm1.1Doel/Clcnkbtm1.1Doel
involves: 129S1/Sv * 129X1/SvJ
abnormal distal convoluted tubule morphology J:259639
abnormal juxtaglomerular apparatus morphology J:259639
abnormal loop of Henle ascending limb thick segment morphology J:259639
abnormal renal sodium ion transport J:259639
abnormal renal transport J:259639
abnormal urine homeostasis J:259639
alkalemia J:259639
alkalosis J:259639
decreased physiological sensitivity to xenobiotic J:259639
decreased urine osmolality J:259639
dilated distal convoluted tubule J:259639
hydronephrosis J:259639
hypokalemia J:259639
increased urine magnesium level J:259639
increased urine prostaglandin level J:259639
juxtaglomerular cell hyperplasia J:259639
polyuria J:259639
postnatal growth retardation J:259639
premature death J:259639
normal renal/urinary system phenotype J:259639
small kidney J:259639

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory