Hacl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hacl1
2-hydroxyacyl-CoA lyase 1
MGI:1929657

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hacl1^tm1.1Pvv/Hacl1^tm1.1Pvv involves: 129S/SvEvBrd * Swiss Webster	abnormal enzyme/coenzyme activity	J:255067
	abnormal fatty acid oxidation	J:255067
	abnormal liver morphology	J:255067
	abnormal urine homeostasis	J:255067
	astrocytosis	J:255067
	normal behavior/neurological phenotype	J:255067
	decreased abdominal adipose tissue amount	J:255067
	decreased liver glycogen level	J:255067
	decreased liver triglyceride level	J:255067
	enlarged liver	J:255067
	normal homeostasis/metabolism phenotype	J:255067
	increased circulating alkaline phosphatase level	J:255067
	increased fatty acids level	J:255067
	increased liver weight	J:255067
	increased percent body fat/body weight	J:255067
	increased susceptibility to diet-induced hepatic steatosis	J:255067
	increased susceptibility to weight loss	J:255067
	normal liver/biliary system phenotype	J:255067
	normal nervous system phenotype	J:255067
Hacl1^{tm1b(KOMP)Wtsi}/Hacl1^{tm1b(KOMP)Wtsi} C57BL/6N-Hacl1^{tm1b(KOMP)Wtsi}/Ucd	abnormal eye morphology	J:211773
	enlarged heart	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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