About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp2r1a
protein phosphatase 2, regulatory subunit A, alpha
MGI:1926334
10 phenotypes from 4 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
\Ppp2r1atm1.1Wltr/\Ppp2r1atm1.2Wltr
\Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 * CBA * FVB/NCrl 		ataxia J:175748
hunched posture J:175748
premature death J:175748
weight loss J:175748
\Ppp2r1atm1.2Wltr/\Ppp2r1a+
FVB.129S1-Ppp2r1atm1.2Wltr 		increased incidence of tumors by chemical induction J:175748
increased lung tumor incidence J:175748
\Ppp2r1atm1.2Wltr/\Ppp2r1atm1.2Wltr
FVB.129S1-Ppp2r1atm1.2Wltr 		embryonic lethality, complete penetrance J:175748
\Ppp2r1atm1.2Wltr/\Ppp2r1atm2.1Wltr
FVB.129-Ppp2r1atm1.2Wltr/Ppp2r1atm2.1Wltr 		increased incidence of tumors by chemical induction J:175748
increased lung adenocarcinoma incidence J:175748
increased lung adenoma incidence J:175748
increased lung tumor incidence J:175748
\Ppp2r1atm2.1Wltr/\Ppp2r1a+
FVB.129-Ppp2r1atm2.1Wltr 		increased incidence of tumors by chemical induction J:175748
increased lung tumor incidence J:175748
\Ppp2r1atm2.1Wltr/\Ppp2r1atm2.1Wltr
FVB.129-Ppp2r1atm2.1Wltr 		no abnormal phenotype detected J:175748
\Ppp2r1atm3.1Wltr/\Ppp2r1atm3.1Wltr
FVB.129-Ppp2r1atm3.1Wltr 		no abnormal phenotype detected J:175748
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory