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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp2r1a
protein phosphatase 2, regulatory subunit A, alpha
MGI:1926334
10 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ppp2r1atm1.1Wltr/Ppp2r1atm1.2Wltr
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 * CBA * FVB/NCrl 		ataxia J:175748
hunched posture J:175748
premature death J:175748
weight loss J:175748
Ppp2r1atm1.2Wltr/Ppp2r1a+
FVB.129S1-Ppp2r1atm1.2Wltr 		increased incidence of tumors by chemical induction J:175748
increased lung tumor incidence J:175748
Ppp2r1atm1.2Wltr/Ppp2r1atm1.2Wltr
FVB.129S1-Ppp2r1atm1.2Wltr 		embryonic lethality, complete penetrance J:175748
Ppp2r1atm1.2Wltr/Ppp2r1atm2.1Wltr
FVB.129-Ppp2r1atm1.2Wltr/Ppp2r1atm2.1Wltr 		increased incidence of tumors by chemical induction J:175748
increased lung adenocarcinoma incidence J:175748
increased lung adenoma incidence J:175748
increased lung tumor incidence J:175748
Ppp2r1atm2.1Wltr/Ppp2r1a+
FVB.129-Ppp2r1atm2.1Wltr 		increased incidence of tumors by chemical induction J:175748
increased lung tumor incidence J:175748
Ppp2r1atm2.1Wltr/Ppp2r1atm2.1Wltr
FVB.129-Ppp2r1atm2.1Wltr 		no abnormal phenotype detected J:175748
Ppp2r1atm3.1Wltr/Ppp2r1atm3.1Wltr
FVB.129-Ppp2r1atm3.1Wltr 		no abnormal phenotype detected J:175748
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory