29 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Med12tm1.1Hsch/Y involves: 129S6/SvEvTac * C57BL/6NCrl	no abnormal phenotype detected	J:166040
Med12tm1.1Hsch/Med12+ Tg(CMV-cre)1Cgn/0 involves: 129S6/SvEvTac * C57BL/6	abnormal neural tube morphology	J:166045
	abnormal neurocranium morphology	J:166045
	abnormal vertebral spinous process morphology	J:166045
	absent vertebral arch	J:166045
	craniorachischisis	J:166045
	curly tail	J:166045
	embryonic lethality during organogenesis, incomplete penetrance	J:166045
	exencephaly	J:166045
	prenatal lethality, incomplete penetrance	J:166045
Med12tm1.1Hsch/Med12tm1.1Hsch involves: 129S6/SvEvTac * C57BL/6NCrl	no abnormal phenotype detected	J:166040
Med12tm1.2Hsch/Y chimera involves: 129S6/SvEvTac * C57BL/6NCr	absent anterior visceral endoderm	J:166040
	embryonic lethality between implantation and somite formation, complete penetrance	J:166040
Med12tm1Hsch/Y chimera involves: 129S6/SvEvTac * C57BL/6NCr	abnormal dorsal-ventral polarity of the somites	J:166040
	abnormal first pharyngeal arch morphology	J:166040
	abnormal head mesenchyme morphology	J:166040
	abnormal heart development	J:166040
	abnormal neural crest cell migration	J:166040
	abnormal neural tube morphology	J:166040
	abnormal pharyngeal arch morphology	J:166040
	abnormal somite development	J:166040
	abnormal somite shape	J:166040
	absent second pharyngeal arch	J:166040
	absent third pharyngeal arch	J:166040
	caudal body truncation	J:166040
	decreased somite size	J:166040
	embryonic lethality during organogenesis, complete penetrance	J:166040
	embryonic lethality, complete penetrance	J:166040
	failure of heart looping	J:166040
	kinked neural tube	J:166040
	open neural tube	J:166040