Nol3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nol3
nucleolar protein 3 (apoptosis repressor with CARD domain)
MGI:1925938

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nol3^em1(IMPC)Mbp/Nol3^em1(IMPC)Mbp C57BL/6N-Nol3^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged kidney	J:211773
	enlarged lymph nodes	J:211773
	enlarged ovary	J:211773
	enlarged seminal vesicle	J:211773
	enlarged spleen	J:211773
	small kidney	J:211773
	small spleen	J:211773
Nol3^tm1.1Rnkt/Nol3^tm1.1Rnkt B6.129-Nol3^tm1.1Rnkt	abnormal lung vasculature morphology	J:193803
	abnormal pulmonary pressure	J:193803
	decreased cell proliferation	J:193803
	decreased susceptibility to injury	J:193803
	increased apoptosis	J:193803
Nol3^tm1Rvh/Nol3^tm1Rvh involves: C57BL/6	abnormal lung weight	J:121501
	cardiac fibrosis	J:121501
	normal cardiovascular system phenotype	J:121501
	decreased ventricle muscle contractility	J:121501
	dilated heart left ventricle	J:121501
	increased cardiomyocyte apoptosis	J:121501
	increased myocardial infarct size	J:121501

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23