Skap1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Skap1
src family associated phosphoprotein 1
MGI:1925723

9 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Skap1^em1(IMPC)Mbp/Skap1^em1(IMPC)Mbp C57BL/6NCrl-Skap1^em1(IMPC)Mbp/MbpMmucd	increased lean body mass	J:211773
	increased total body fat amount	J:211773
Skap1^Gt713Lex/Skap1^Gt713Lex B6.129S5-Skap1^Gt713Lex	abnormal CD4-positive, alpha-beta T cell physiology	J:126545
	abnormal immune system physiology	J:126545
	abnormal T cell physiology	J:126545
	decreased interferon-gamma secretion	J:126545
	decreased interleukin-2 secretion	J:126545
	decreased T cell proliferation	J:126545
	normal immune system phenotype	J:126545

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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