Apex2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apex2
apurinic/apyrimidinic endonuclease 2
MGI:1924872

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apex2^em1(IMPC)H/Y C57BL/6NTac-Apex2^em1(IMPC)H/H	abnormal coat/hair pigmentation	J:211773
Apex2^em1(IMPC)H/Apex2^em1(IMPC)H C57BL/6NTac-Apex2^em1(IMPC)H/H	abnormal snout morphology	J:211773
	decreased erythrocyte cell number	J:211773
	decreased locomotor activity	J:211773
	decreased lymphocyte cell number	J:211773
	increased mean corpuscular volume	J:211773
	increased neutrophil cell number	J:211773
Apex2^tm1Yun/Y B6.129S-Apex2^tm1Yun	decreased B cell number	J:95267
	decreased birth weight	J:95267
	decreased erythrocyte cell number	J:95267
	decreased leukocyte cell number	J:95267
	decreased splenocyte proliferation	J:95267
	decreased T cell number	J:95267
	decreased thymocyte number	J:95267
	increased cellular sensitivity to X-ray irradiation	J:95267
	postnatal growth retardation	J:95267
	thymus atrophy	J:95267

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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