Pbrm1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pbrm1
polybromo 1
MGI:1923998

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pbrm1^{tm1b(EUCOMM)Wtsi}/Pbrm1⁺ C57BL/6N-Pbrm1^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal gait	J:211773
	abnormal kidney morphology	J:211773
	decreased circulating creatinine level	J:211773
	decreased prepulse inhibition	J:211773
	increased mean platelet volume	J:211773
Pbrm1^{tm1b(EUCOMM)Wtsi}/Pbrm1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pbrm1^{tm1b(EUCOMM)Wtsi}/Ieg	preweaning lethality, complete penetrance	J:211773
Pbrm1^tm1Rtj/Pbrm1^tm1Rtj Not Specified	abnormal interventricular septum morphology	J:95332
	abnormal placenta labyrinth morphology	J:95332
	abnormal spongiotrophoblast layer morphology	J:95332
	abnormal trophoblast giant cell morphology	J:95332
	lethality throughout fetal growth and development, complete penetrance	J:95332
	small liver	J:95332
	small lung	J:95332
	ventricular hypoplasia	J:95332
Pbrm1^tm1Zhwa/Pbrm1^tm1Zhwa Tg(Cd4-cre)1Cwi/? involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal T-helper 2 cell differentiation	J:236906
	decreased T cell proliferation	J:236906
	normal immune system phenotype	J:236906
	increased interleukin-4 secretion	J:236906
	increased interleukin-10 secretion	J:236906

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23