Crtc2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crtc2
CREB regulated transcription coactivator 2
MGI:1921593

10 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crtc2^tm1.1Khk/Crtc2^tm1.1Khk involves: C57BL/6 * C57BL/6J * FVB/N	abnormal glucose homeostasis	J:151618
	abnormal liver physiology	J:151618
	decreased circulating corticosterone level	J:151618
	decreased glycogen level	J:151618
Crtc2^{tm1a(EUCOMM)Wtsi}/Crtc2^{tm1a(EUCOMM)Wtsi} B6.B6N-Crtc2^{tm1a(EUCOMM)Wtsi}	increased adipocyte glucose uptake	J:229999
Crtc2^tm1Mmy/Crtc2^tm1Mmy involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	decreased circulating insulin level	J:157556
	decreased fasting circulating glucose level	J:157556
	decreased hepatic glucose production	J:157556
	impaired gluconeogenesis	J:157556
	increased insulin sensitivity	J:157556

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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