Spink5 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spink5
serine peptidase inhibitor, Kazal type 5
MGI:1919682

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F2rl1^tm1Cgh/F2rl1^tm1Cgh Spink5^tm1Hov/Spink5^tm1Hov involves: 129P2/OlaHsd * 129S4/SvJae	abnormal epidermis stratum corneum morphology	J:180855
	abnormal skin morphology	J:180855
	abnormal vibrissa morphology	J:180855
	acanthosis	J:180855
	dehydration	J:180855
	neonatal lethality, complete penetrance	J:180855
Klk6^tm1Gsot/Klk6^tm1Gsot Spink5^tm1Drh/Spink5^tm1Drh involves: 129P2/OlaHsd * C57BL/6	abnormal cytokine level	J:289877
	abnormal epidermis stratum corneum morphology	J:289877
	abnormal skin morphology	J:289877
	abnormal vibrissa morphology	J:289877
	decreased inflammatory response	J:289877
	epidermal desquamation	J:289877
	impaired skin barrier function	J:289877
	normal integument phenotype	J:289877
	neonatal lethality, complete penetrance	J:289877

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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