83 phenotypes from 3 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ Prdm16tm1.1Brsp/Prdm16tm1.1Brsp B6.Cg-Prdm16tm1.1Brsp A1cfTg(Myh6-cre/Esr1*)1Jmk	normal cardiovascular system phenotype	J:326525
Prdm16csp1/Prdm16+ FVB.C-Prdm16csp1	cleft secondary palate	J:157112
Prdm16csp1/Prdm16csp1 FVB.C-Prdm16csp1	abnormal choroid plexus morphology	J:157112
	abnormal heart morphology	J:157112
	abnormal heart ventricle morphology	J:157112
	abnormal lung morphology	J:157112
	abnormal mandible morphology	J:157112
	abnormal nasal bone morphology	J:157112
	abnormal palatal shelf elevation	J:157112
	abnormal snout morphology	J:157112
	abnormal sublingual duct morphology	J:157112
	abnormal sublingual gland morphology	J:157112
	abnormal submandibular duct morphology	J:157112
	abnormal tongue morphology	J:157112
	abnormal tongue position	J:157112
	cleft secondary palate	J:157112
	distended abdomen	J:157112
	mandible hypoplasia	J:157112
	micrognathia	J:157112
	narrow maxilla	J:157112
	narrow snout	J:157112
	neonatal lethality, complete penetrance	J:157112
	premature bone ossification	J:157112
	pulmonary hypoplasia	J:157112
	respiratory distress	J:157112
	respiratory failure	J:157112
	retina fold	J:157112
	short maxilla	J:157112
	short Meckel's cartilage	J:157112
	short nasal bone	J:157112
	short snout	J:157112
	small lung	J:157112
	small mandible	J:157112
	submandibular gland hypoplasia	J:157112
	ventricular hypoplasia	J:157112
Prdm16csp1/Prdm16csp1 involves: BALB/c * C57BL/6J * FVB/NJ	cleft secondary palate	J:157112
	neonatal lethality, complete penetrance	J:157112
	respiratory failure	J:157112
	submucous cleft palate	J:157112
Prdm16csp1/Prdm16csp1 Not Specified	cleft secondary palate	J:75360
Prdm16csp1/Prdm16Gt(OST67423)Lex involves: 129S5/SvEvBrd * BALB/c * C57BL/6J * FVB/NJ	cleft secondary palate	J:157112
Prdm16Gt(OST67423)Lex/Prdm16+ involves: 129S5/SvEvBrd * C57BL/6J	increased leukocyte cell number	J:103485
Prdm16Gt(OST67423)Lex/Prdm16Gt(OST67423)Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal heart morphology	J:157112
	abnormal tongue morphology	J:157112
	abnormal tongue position	J:157112
	cleft secondary palate	J:157112
	perinatal lethality, complete penetrance	J:103485
	pointed snout	J:157112
	prenatal lethality, incomplete penetrance	J:103485
	ventricular hypoplasia	J:157112
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp B6.129-Prdm16tm1.1Brsp	no abnormal phenotype detected	J:208683
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp Myf5tm1(cre)Mrc/Myf5+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal brown adipose tissue morphology	J:213153
	abnormal brown adipose tissue thermogenesis	J:213153
	abnormal cellular respiration	J:213153
	abnormal interscapular fat pad morphology	J:213153
	abnormal oxygen consumption	J:213153
	decreased body fat mass	J:213153
	decreased body length	J:213153
	decreased body weight	J:213153
	decreased brown fat lipid droplet number	J:213153
	decreased fat cell mitochondrial DNA content	J:213153
	decreased lean body mass	J:213153
	decreased mitochondrial number	J:213153
	impaired adaptive thermogenesis	J:213153
	improved glucose tolerance	J:213153
	increased brown fat cell lipid droplet size	J:213153
	increased interscapular fat pad weight	J:213153
	whitened brown adipose tissue morphology	J:213153
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp Tg(Adipoq-cre)1Evdr/0 involves: 129/Sv * C57BL/6 * FVB/N	abnormal adipose tissue distribution	J:208683
	abnormal adipose tissue morphology	J:208683
	abnormal adipose tissue physiology	J:208683
	abnormal brown adipose tissue thermogenesis	J:208683
	abnormal oxygen consumption	J:208683
	decreased adipocyte glucose uptake	J:208683
	hepatic steatosis	J:208683
	increased circulating insulin level	J:208683
	increased fat cell size	J:208683
	increased liver triglyceride level	J:208683
	increased macrophage cell number	J:208683
	increased respiratory quotient	J:208683
	increased subcutaneous adipose tissue amount	J:208683
	increased susceptibility to weight gain	J:208683
	increased total body fat amount	J:208683
	insulin resistance	J:208683
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp Tg(myl7.L-cre)1118Tmhn/0 involves: 129 * C57BL/6J * MF1	abnormal cardiovascular system physiology	J:326525
	abnormal heart apex morphology	J:326525
	abnormal heart development	J:326525
	abnormal heart echocardiography feature	J:326525
	cardiomyopathy	J:326525
	decreased cardiac muscle contractility	J:326525
	decreased fetal cardiomyocyte proliferation	J:326525
	dilated heart left ventricle	J:326525
	increased heart left ventricle size	J:326525
	postnatal lethality, complete penetrance	J:326525
	thin interventricular septum	J:326525
	thin left ventricle myocardium compact layer	J:326525
Prdm16tm1.1Brsp/Prdm16tm1.1Brsp Tg(Tnnt2-cre)5Blh/0 involves: 129 * C57BL/6 * C57BL/6J * DBA/2	dilated heart left ventricle	J:326525
	postnatal lethality, complete penetrance	J:326525