Mutyh Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mutyh
mutY DNA glycosylase
MGI:1917853

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Msh2^tm1Mak/Msh2⁺ Mutyh^tm1Jhmi/Mutyh^tm1Jhmi Ogg1^tm1Tld/Ogg1^tm1Tld involves: 129 * C57BL/6J	increased lung adenocarcinoma incidence	J:89742
	increased lung adenoma incidence	J:89742
	increased lymphoma incidence	J:89742
	increased ovary tumor incidence	J:89742
	increased tumor incidence	J:89742
	premature death	J:89742
Msh2^tm1Mak/Msh2^tm1Mak Mutyh^tm1Jhmi/Mutyh^tm1Jhmi Ogg1^tm1Tld/Ogg1^tm1Tld involves: 129 * C57BL/6J	increased lung adenoma incidence	J:89742
	increased lymphoma incidence	J:89742
	increased tumor incidence	J:89742
	premature death	J:89742
Mutyh^tm1Jhmi/Mutyh^tm1Jhmi Ogg1^tm1Tld/Ogg1^tm1Tld involves: 129 * C57BL/6J	increased hemangioma incidence	J:89742
	increased lung adenoma incidence	J:89742
	increased lung tumor incidence	J:89742
	increased lymphoma incidence	J:89742
	increased ovary tumor incidence	J:89742
	increased tumor incidence	J:89742
	premature death	J:89742
Mutyh^tm1Yun/Mutyh^tm1Yun Nudt1^tm1Tts/Nudt1^tm1Tts Ogg1^tm1Yun/Ogg1^tm1Yun B6JJcl.129-Mutyh^tm1Yun Nudt1^tm1Tts Ogg1^tm1Yun	increased tumor incidence	J:193978
Mutyh^tm1Yun/Mutyh^tm1Yun Ogg1^tm1Yun/Ogg1^tm1Yun involves: 129S/SvEv * C57BL/6JJcl	decreased susceptibility to neuronal excitotoxicity	J:193978

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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