Fndc5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fndc5
fibronectin type III domain containing 5
MGI:1917614

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fndc5^em21Gpt/Fndc5^em21Gpt C57BL/6JGpt-Fndc5^em21Cd/Gpt	abnormal behavior	J:247171
	abnormal circulating enzyme level	J:247171
	abnormal circulating lipid level	J:247171
	abnormal fatty acid oxidation	J:247171
	normal growth/size/body region phenotype	J:247171
	impaired autophagy	J:247171
	increased susceptibility to diet-induced hepatic steatosis	J:247171
	increased susceptibility to diet-induced obesity	J:247171, J:291193
	increased susceptibility to hepatic steatosis	J:247171
	increased susceptibility to induced morbidity/mortality	J:291193
Fndc5^tm1.1Brsp/Fndc5^tm1.1Brsp involves: C57BL/6J	abnormal osteocyte lacuna morphology	J:269575
	abnormal osteocyte morphology	J:269575
	decreased bone resorption	J:269575
	decreased susceptibility to osteoporosis	J:269575
	increased trabecular bone connectivity density	J:269575
	increased trabecular bone mass	J:269575
	normal skeleton phenotype	J:269575

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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