Arhgef12 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgef12
Rho guanine nucleotide exchange factor 12
MGI:1916882

12 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgef12^tm1.1Wet/Arhgef12^tm1.1Wet Tg(Lck-cre)548Jxm/0 involves: 129 * C57BL/6 * CBA	abnormal T cell proliferation	J:149560
Arhgef12^{tm1b(KOMP)Wtsi}/Arhgef12⁺ C57BL/6N-Arhgef12^{tm1b(KOMP)Wtsi}/Tcp	abnormal embryo size	J:211773
	abnormal heart morphology	J:211773
	abnormal heart shape	J:211773
	decreased locomotor activity	J:211773
	embryonic growth retardation	J:211773
	enlarged heart	J:211773
	increased prepulse inhibition	J:211773
Arhgef12^{tm1b(KOMP)Wtsi}/Arhgef12^{tm1b(KOMP)Wtsi} C57BL/6N-Arhgef12^{tm1b(KOMP)Wtsi}/Tcp	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Arhgef12^tm1Sgkd/Arhgef12^tm1Sgkd involves: 129 * C57BL/6J	prenatal lethality, incomplete penetrance	J:198274

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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