Pofut2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pofut2
protein O-fucosyltransferase 2
MGI:1916863

20 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pofut2^{Gt(OST231463)Lex}/Pofut2^{Gt(OST231463)Lex} involves: 129S5/SvEvBrd	embryonic lethality, complete penetrance	J:165751
Pofut2^{Gt(OST231463)Lex}/Pofut2^{Gt(RST434)Byg} involves: 129P2/OlaHsd * 129S5/SvEvBrd	embryonic lethality, complete penetrance	J:165751
Pofut2^{Gt(RST434)Byg}/Pofut2^{Gt(RST434)Byg} involves: 129P2/OlaHsd	abnormal anterior visceral endoderm morphology	J:165751
	abnormal ectoderm development	J:165751
	abnormal embryo development	J:165751
	abnormal embryonic epiblast morphology	J:165751
	abnormal embryonic erythropoiesis	J:165751
	abnormal extraembryonic ectoderm morphology	J:165751
	abnormal physiological response to xenobiotic	J:165751
	abnormal Reichert's membrane morphology	J:165751
	abnormal vascular endothelial cell differentiation	J:165751
	absent primitive node	J:165751
	disorganized embryonic tissue	J:165751
	disorganized extraembryonic tissue	J:165751
	embryonic lethality between implantation and somite formation, complete penetrance	J:165751
Pofut2^tm2.2Bch/Pofut2^tm2.2Bch B6.Cg-Pofut2^tm2.2Bch	abnormal anterior visceral endoderm morphology	J:234992
	abnormal embryo morphology	J:234992
	abnormal extraembryonic tissue morphology	J:234992
	abnormal visceral endoderm morphology	J:234992
	absent mesoderm	J:234992
	disorganized embryonic tissue	J:234992
	disorganized extraembryonic tissue	J:234992
	embryonic lethality during organogenesis, complete penetrance	J:234992
Pofut2^tm2Bch/Pofut2^tm2Bch involves: C57BL/6	embryonic lethality	J:234992

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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