Dusp22 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dusp22
dual specificity phosphatase 22
MGI:1915926

27 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Dusp22^tm1Tht/Dusp22^tm1Tht B6.129S7-Dusp22^tm1Tht	abnormal B cell activation	J:213253
	abnormal cytokine level	J:213253
	abnormal glomerular mesangium morphology	J:213253
	abnormal renal glomerulus morphology	J:213253
	abnormal T cell activation	J:213253
	decreased B cell proliferation	J:213253
	decreased IgG3 level	J:213253
	decreased IgM level	J:213253
	decreased immunoglobulin level	J:213253
	enlarged spleen	J:213253
	increased circulating interferon-gamma level	J:213253
	increased circulating interleukin-6 level	J:213253
	increased circulating interleukin-17 level	J:213253
	increased circulating tumor necrosis factor level	J:213253
	increased inflammatory response	J:213253
	increased interferon-gamma secretion	J:213253
	increased interleukin-2 secretion	J:213253
	increased interleukin-4 secretion	J:213253
	increased interleukin-17 secretion	J:213253
	increased renal glomerulus lobularity	J:213253
	increased spleen white pulp amount	J:213253
	increased susceptibility to autoimmune disorder	J:213253
	increased susceptibility to experimental autoimmune encephalomyelitis	J:213253
	increased T cell proliferation	J:213253
	kidney inflammation	J:213253
	liver inflammation	J:213253
	lung inflammation	J:213253

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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