Rpa1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rpa1
replication protein A1
MGI:1915525

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rpa1^{tm1b(KOMP)Wtsi}/Rpa1⁺ C57BL/6N-Rpa1^{tm1b(KOMP)Wtsi}/J	decreased circulating free fatty acids level	J:211773
	decreased circulating glucose level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	increased heart weight	J:211773
	increased mean corpuscular volume	J:211773
Rpa1^{tm1b(KOMP)Wtsi}/Rpa1^{tm1b(KOMP)Wtsi} C57BL/6N-Rpa1^{tm1b(KOMP)Wtsi}/J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Rpa1^tm1Wed/Rpa1⁺ involves: 129/Sv * C57BL/6J * SJL	abnormal definitive hematopoiesis	J:99303
	chromosome breakage	J:99303
	increased lymphocyte cell number	J:99303
	increased lymphoma incidence	J:99303
	premature death	J:99303
Rpa1^tm1Wed/Rpa1^tm1Wed involves: 129/Sv * C57BL/6J * SJL	decreased cell proliferation	J:99303
Rpa1^tm1Wed/Rpa1^tm1Wed involves: 129/Sv * C57BL/6J * SJL	embryonic lethality before implantation, complete penetrance	J:99303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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