About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cops8
COP9 signalosome subunit 8
MGI:1915363
10 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cops8tm1.1Nwe/Cops8tm1.1Nwe
involves: C57BL/6
abnormal inner cell mass proliferation J:126339
decreased embryo size J:126339
embryonic growth retardation J:126339
prenatal lethality, complete penetrance J:126339
Cops8tm1Nwe/Cops8tm1.1Nwe
involves: 129S1/Sv * C57BL/6
abnormal cell cycle J:126339
Cops8tm1Nwe/Cops8tm1.1Nwe
Tg(Cd4-cre)1Cwi/?
involves: 129S1/Sv * C57BL/6 * DBA/2
abnormal CD4-positive, alpha-beta T cell physiology J:126339
abnormal T cell activation J:126339
decreased interleukin-2 secretion J:126339
decreased T cell number J:126339
decreased T cell proliferation J:126339

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory