Plpp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plpp3
phospholipid phosphatase 3
MGI:1915166

39 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plpp3^{tm1b(EUCOMM)Hmgu}/Plpp3⁺ C57BL/6N-Plpp3^{tm1b(EUCOMM)Hmgu}/Cnrm	decreased mean corpuscular hemoglobin	J:211773
	increased circulating creatinine level	J:211773
Plpp3^{tm1b(EUCOMM)Hmgu}/Plpp3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Plpp3^{tm1b(EUCOMM)Hmgu}/Cnrm	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Plpp3^tm1Stw/Plpp3^tm1Stw either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal allantois morphology	J:84753
	abnormal embryo turning	J:84753
	abnormal extraembryonic tissue morphology	J:84753
	abnormal phospholipid level	J:84753
	abnormal vasculogenesis	J:84753
	abnormal vitelline vascular remodeling	J:84753
	abnormal vitelline vasculature morphology	J:84753
	absent vitelline blood vessels	J:84753
	disorganized yolk sac vascular plexus	J:84753
	embryonic growth retardation	J:84753
	embryonic lethality during organogenesis, complete penetrance	J:84753
	failure of chorioallantoic fusion	J:84753
	hemorrhage	J:84753
	pale yolk sac	J:84753
Plpp3^tm1Stw/Plpp3^tm1Stw involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal anterior visceral endoderm morphology	J:84753
	abnormal embryonic tissue morphology	J:84753
	abnormal gastrulation	J:84753
	abnormal neural tube morphology	J:84753
	abnormal notochord morphology	J:84753
	abnormal primitive node morphology	J:84753
	abnormal primitive streak morphology	J:84753
	abnormal rostral-caudal axis patterning	J:84753
	embryonic-extraembryonic boundary constriction	J:84753
	increased axial mesoderm size	J:84753
	increased somite number	J:84753
	rostral body truncation	J:84753
	rostral-caudal axis duplication	J:84753
	short rostral-caudal axis	J:84753
Plpp3^tm2Stw/Plpp3^tm2Stw involves: 129S1/Sv * C57BL/6J	abnormal allantois morphology	J:142493
	abnormal gastrulation	J:142493
	abnormal vitelline vascular remodeling	J:142493
	embryonic growth retardation	J:142493
	failure of chorioallantoic fusion	J:142493
	open neural tube	J:142493
	prenatal lethality	J:142493
Plpp3^tm3.1Stw/Plpp3^tm3.1Stw involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal allantois morphology	J:125025
	abnormal embryo turning	J:125025
	abnormal neural fold morphology	J:125025
	abnormal vitelline vasculature morphology	J:125025
	embryonic growth retardation	J:125025
	enlarged allantois	J:125025
	failure of chorioallantoic fusion	J:125025
	hemorrhage	J:125025
	kinked neural tube	J:125025
	prenatal lethality, complete penetrance	J:125025
Plpp3^tm3Stw/Plpp3^tm3Stw involves: 129S1/Sv * C57BL/6J	no abnormal phenotype detected	J:125025

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23