Bcs1l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bcs1l
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
MGI:1914071

47 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bcs1l^{tm1.1(KOMP)Vlcg}/Bcs1l^{tm1.1(KOMP)Vlcg} B6N(Cg)-Bcs1l^{tm1.1(KOMP)Vlcg}/Ucd	abnormal egg cylinder morphology	J:279207
	absent head fold	J:279207
	absent primitive node	J:279207
	decreased embryo size	J:279207
	embryonic growth arrest	J:279207
	embryonic lethality prior to organogenesis	J:279207
	embryonic lethality, complete penetrance	J:279207
	failure of primitive streak formation	J:279207
	failure to gastrulate	J:279207
Bcs1l^{tm1.1(KOMP)Vlcg}/Bcs1l^{tm1.1(KOMP)Vlcg} C57BL/6N-Bcs1l^{tm1.1(KOMP)Vlcg}/Ucd	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Bcs1l^tm1.1Levp/Bcs1l^tm1.1Levp B6.129-Bcs1l^tm1.1Levp	abnormal enzyme/coenzyme level	J:273501
	abnormal hepatocyte mitochondrial morphology	J:273501
	abnormal hepatocyte morphology	J:273501
	abnormal liver morphology	J:273501
	abnormal liver physiology	J:273501
	abnormal macrophage morphology	J:273501
	abnormal mitochondrial crista morphology	J:273501
	abnormal mitochondrial physiology	J:273501
	abnormal portal triad morphology	J:273501
	decreased circulating arginine level	J:273501
	decreased circulating glucose level	J:273501
	hepatic necrosis	J:273501
	increased circulating alanine transaminase level	J:273501
	increased circulating alkaline phosphatase level	J:273501
	increased circulating citrulline level	J:273501
	increased circulating ornithine level	J:273501
	increased macrophage cell number	J:273501
	increased neutrophil cell number	J:273501
	ketosis	J:273501
	liver fibrosis	J:273501
	liver inflammation	J:273501
	premature death	J:273501
Bcs1l^tm1.1Levp/Bcs1l^tm1.1Levp involves: 129 * 129S6/SvEvTac * C57BL/6	abnormal cellular respiration	J:189652
	abnormal liver morphology	J:189652
	abnormal mitochondrial physiology	J:189652
	abnormal proximal convoluted tubule morphology	J:189652
	decreased body weight	J:189652
	decreased Leydig cell number	J:189652
	decreased liver glycogen level	J:189652
	decreased locomotor activity	J:189652
	hunched posture	J:189652
	increased circulating lactate level	J:189652
	increased liver iron level	J:189652
	increased mitochondrial size	J:189652
	liver fibrosis	J:189652
	microvesicular hepatic steatosis	J:189652
	premature death	J:189652
	slow postnatal weight gain	J:189652
	small liver	J:189652
	weight loss	J:189652

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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