Cox14 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cox14
cytochrome c oxidase assembly protein 14
MGI:1913629

43 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Cox14^em83Cecad/Cox14^em83Cecad C57BL/6N-Cox14^em83Cecad	abnormal CD4-negative NK T cell number	J:354134
	abnormal cellular cholesterol metabolism	J:354134
	abnormal eye vasculature morphology	J:354134
	abnormal hepatocyte mitochondrial morphology	J:354134
	abnormal hepatocyte morphology	J:354134
	abnormal innate immunity	J:354134
	abnormal mitochondrial ATP synthesis coupled electron transport	J:354134
	abnormal mitochondrial physiology	J:354134
	abnormal NK cell number	J:354134
	abnormal retina blood vessel pattern	J:354134
	abnormal rod electrophysiology	J:354134
	abnormal skeletal muscle regeneration	J:354134
	abnormal splenic cell ratio	J:354134
	abnormal translation	J:354134
	centrally nucleated skeletal muscle fibers	J:354134
	decreased a-wave amplitude	J:354134
	decreased body weight	J:354134
	decreased heart left ventricle size	J:354134
	decreased hepatocyte respiration	J:354134
	decreased retina photoreceptor cell number	J:354134
	decreased total retina thickness	J:354134
	disorganized mitochondrial cristae	J:354134
	focal hepatic necrosis	J:354134
	increased CD8-positive, alpha-beta T cell number	J:354134
	increased circulating alanine transaminase level	J:354134
	increased circulating aspartate transaminase level	J:354134
	increased circulating cholesterol level	J:354134
	increased circulating creatinine level	J:354134
	increased heart left ventricle anterior wall thickness	J:354134
	increased heart left ventricle muscle contractility	J:354134
	increased heart left ventricle posterior wall thickness	J:354134
	increased Ly6C-positive immature NK cell number	J:354134
	increased myocardial fiber size	J:354134
	increased retina apoptosis	J:354134
	increased retina vascular tortuosity	J:354134
	liver inflammation	J:354134
	myocardial fiber degeneration	J:354134
	oxidative stress	J:354134
	premature death	J:354134
	preweaning lethality, incomplete penetrance	J:354134
	retina degeneration	J:354134
	thin retina outer nuclear layer	J:354134
	thin retina outer plexiform layer	J:354134

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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